Titrating the dose of steroids to match the severity of inflammation results in a healthier patient with fewer emergency room visits and significantly fewer exacerbations (Green 2002).

Studies have confirmed that routine monitoring of FENO levels makes it possible to titrate the steroid dose according to the patient's specific need (Pijnenburg 2005; Smith 2005).

Monitoring levels of FENO can significantly reduce maintenance doses of inhaled steroids without compromising asthma control(Smith 2005)
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Compared to conventional treatment guidelines, steroid titration based on FENO levels and symptoms improved asthma prognosis as defined by less hyper-responsiveness and less inflammation (Pijnenburg 2005).