NIOX MINO® Nasal

NIOX MINO Nasal mode is a Research application and can be used to determine the concentration of nitric oxide (NO) in gas aspirated from one nostril, using passive sampling.

The concept comprises of a nasal olive with tubing, which is connected to a bacterial/viral filter and a dedicated NIOX MINO Nasal software application.

Nasal NO has been studied in for example Cystic Fibrosis (CF) and Primary Ciliary Dyskinesia (PCD). According to the literature* patients with PCD have markedly lower nasal NO values than healthy individuals.

*PCD References: 

- Andrew Bush, Rahul Chodhari, Nicola Collins, et al. Primary ciliary dyskinesia: current state of the art. Arch Dis Child 2007;92:1136-1140 doi:10.1136/adc.2006.096958. (Download free full text article)

- Regula Corbelli and Jürg Hammer. Measurement of nasal nitric oxide. Paediatric Respiratory Reviews (2007)8, 269-272. (Download free full text article)

- Jon O. Lundberg. Nitric Oxide and the Paranasal Sinuses. The Anatomical Record 291:1479–1484 (2008). (Download free full text article)

Contact your local distributor or Aerocrine directly for further information regarding nasal NO measurements with NIOX MINO.   

NIOX MINO Nasal Technical Specifications

 For further NIOX MINO technical data refer to the Specifications page

Other nasal NO measurement techniques than aspiration from one nostril have also been investigated using NIOX MINO. A method of nasal exhalations in NIOX MINO using a mask is supported by studies. Please refer to publications [19], [24], [43] and [61] on the reference page. 
These techniques are considered to be purely for exploratory use.